Prehypertension is usually associated with other components of the metabolic syndrome i.e. obesity, glucose intolerance and dyslipidemia. This association is due to common mechanistic pathways and has implications on cardiovascular complications. Diet and exercise with or without drug therapy benefit all components of the metabolic syndrome. Antihypertensive medications may lead to deterioration in glucose tolerance while glucose lowering agents may affect blood pressure. Thus, any discussion about the approach to prehypertension must be done in context to the whole cardio metabolic risk.
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